Some positive double-blind studies
Airaksinen O, et al.:
Effects of infra-red laser irradiation at the trigger points. Scandinavian Journal of Acupuncture & Electro Therapy. 1988; 3: 56-61.
Airaksinen O, et al.:
Effects of laser irradiation at treated and non-treated trigger points. Proc. 4th International Symposium. Acupuncture & Electrotherapy Res. 1988; 13 (4): 238-239.
Antipa C, Nacu M et al.:
Clinical results of the low energy laser action on distal forearm posttraumatic nerve lesions. Laser Therapy. 1996; 1:36.
Antipa C, Moldovan C et al.:
Low power laser in clinical medicine. Personal experience. Laser Journal. 1999, 1 (1). (www.EMLA.net).
Antipa C, Coculescu M et al.:
Treatment of acromegalic arthropathy with low power laser. Laser Journal. 1999, 1 (1): 1. (www.EMLA.net).
Armino L et al.:
Laser therapy in post-episiotomic nevralgie. J Eur Med Laser Ass. 1988; 1(1):7.
Atsumi K et al.:
Biostimulation effect of low-power energy diode laser for pain relief. Lasers Surg Med. 1987; 7: 77.
Barabas K et al.:
Controlled clinical and experimental examinations on rheumatoid arthritis patients and synovial membranes performed with neodym phosphate glas laser irradiation. Proc. 7th Congr Internat Soc for Laser Surg Med, Munich June 1987. Abstract no. 216a.
Barash A et al:.
Helium-Neon laser effects on conditioning-induced oral mucositis in bone marrow transplantation patients. Cancer. 1995; 76 (12): 2550-2556.
Bensadoun R, Franqiun J, Ciais C et al.:
Low energy He/Ne laser in the prevention of radiation-induced mucositis: A multicenter phase III randomized study in patients with head and neck cancer. Support Care Cancer. 1999; 7 (4): 244-252.
de Bie R et al.:
Effect of laser therapy on ankle sprain. Ned T Fysiotherapie. 1989; 99: 4-7.
Bihari I, Mester A.:
The biostimulative effect of low level laser therapy of long-standing crural ulcer using Helium Neon laser, Helium Neon plus infrared lasers and non coherent light: Preliminary report of a randomized double blind comparative study. Laser Therapy. 1989; 1 (2): 97.
Boerner E et al.:
Double-blind study on the efficacy of the lasertherapy. SPIE Proc. 1996. Vol. 2929: 75-79.
Bringmann W.:
Lasertherapie beim chronischen Schultertrauma. DZA. 1998; 4: 109-120.
Carati C, Anderson S, Gannon B, Piller N.:
Treatment of postmastectomy lymphedema with low-level laser therapy. A double blind, placebo-controlled trial. Cancer. 2003; 98 (6): 1114-1122.
Carillo J et al.:
A randomized double-blind clinical trial on the effectiveness of helium-neon laser in the prevention of pain, swelling and trismus after removal of impacted third molars. Int Dent Journ. 1990; 40: 31.
Ceccherelli F et al.:
Diode laser in cervical myofascial pain. A double-blind study versus placebo. The Clin J Pain. 1989; 4: 301-304.
Cheng R.:
Combined treatments of electrotherapy plus soft laser therapy has synergistic effect in pain relief and disease healing. Surgical and Medical Lasers. 1990; 3 (3): 135.
Cho K, Park J, Ko M.:
The effect of low level laser therapy on pressure pain threshold in patients with TMD: A double blind study. J Korean Acad Oral Medicine. 1999; 24 (3): 281-300.
Cieslar G et al.:
Effect of low-power laser radiation in the treatment of the motional system overloading syndromes. SPIE Proc. Vol 3198. 1997: 76-82.
Conconi F, Bientines L, Rogacieri A et al.:
Resultati preliminari di laser terapia sulla patologia sportiva (studio in doppio cieco). Medical Laser Report. 1985; (3): 32-36.
Cowen D et al.:
Low energy helium neon laser in the prevention of oral mucositis in patients undergoing bone marrow transplant: results of a double blind randomized trial. Int J Radiat Oncol Biol Phys. 1997; 38 (4): 697-703.
Eckerdal A, Lehmann Bastian H.:
Can low reactive-level laser therapy be used in the treatment of neurogenic facial pain? A double-blind, placebo controlled investigation of patients with trigeminal neuralgia. Laser Therapy. 1996; 8: 247-252.
Emmanoulidis O et al.:
CW IR low-power laser application significantly accelerates chronic pain relief rehabilitation of professional athletes. A double blind study. Lasers Surg Med. 1986; 6: 173.
England S et al.
Low power laser therapy of shoulder tendonitis. Scand J Rheumat. 1989; 18: 427.
Flöter T, Refisch H.:
Pain treatment with laser. A double blind study. Proc. of the 4th International Symposium. Acupuncture & Electrotherapy Res. 1988; 13(4): 236-237. Also: Schmerzbehandlung mit Laser. Ein Doppelblind Studie. Top Medizin. 1990; 4(4): 52-. (German).
Fructuoso F, Moset J.:
Estudio randomizado doble ciego sobre los efectos bioestimulantes del láser en la irradiación de glándula parótida en pacientes afectos de síndrome de Sjögren. Investigación y Clinica Laser. 1987; 4 (1): 18-25.
Fukuuchi A et al.:
A double-blind trial of low reactive-level laser therapy in the treatment of chronic pain. Laser Therapy. 1999; 10 (2):59-63.
Gelskey S et al.:
The effectiveness of the Nd:YAG laser in the treatment of dentinal hypersensitivity. J Can Dent Assoc. 1993; 59 (4):337-386.
Gerschman J et al.:
Low Level Laser in dentine hypersensitivity. Australian Dent J. 1994; 39: 6.
Goldman J et al.:
Laser therapy of rheumatoid arthritis. Lasers Surg Med. 1980; 1: 93-102.
Gray R et al.:
Physiotherapy in the treatment of temporomandibular joint disorders: a comparative study of four treatment methods. Br Dent J. 1994; 176 (7): 257-261.
Gudmundsen J et al.:
Laserbehandling av epicondylitis humeri og rotatorcuff-syndrom. Dobbelt blindstudie - 200 pasienter. Norsk tidsskrift for idrettsmedisin. 1987; 2: 6. (Norwegian).
Gärtner C.:
Analgesy by low power laser (LPL): a controlled double blind study in ankylosing spondarthritis (SPA). Lasers Surg Med. 1989; Suppl 1:55. Laser Therapy. 1992; (4): 107-115.
Götte S et al.:
Doppelblindstudie zur Überprüfung der Wirksamkeit und Verträglich-keit einer niederenergetischen Lasertherapie bei Patienten mit aktiver Gonarthrose. Jaros Orthopädie. 1995. 12: 3034. (German).
Hahn A, Senja I, Stolbova K, Cocek A.:
Combined laser-EGb 761 tinnitus therapy. Acta Otolarngol Suppl. 2001; 545: 92-93.
Haker E, Lundeberg T.:
Is low-energy laser treatment effective in lateral epicondylalgia? J Pain Symptom Management. 1991; 6 (4): 241-246.
Haruki E, Yamaguchi S.:
Double blind evaluation of low energy laser treatment for painful disease. J Phys Med. 1995; 6: 60-67. (Japanese with English abstract).
Hashimoto K.:
Clinical applications of various lasers in oral surgery. In: Lasers in dentistry. Eds. Yamamoto Y et al. 1989; 63-70. Elsevier Science Publishing B.V, Amsterdam.
Hashimoto T et al.:
Efficacy of laser irradiation on the area near the stellate ganglion is dose-dependent: a double-blind crossover placebo-controlled study. Laser Therapy. 1997; 1(9): 7-11.
Hirschl M, Katzenschlager R, Ammer K et al.:
Double-blind, randomised, placebo controlled LLLT study in patients with primary Raynaud´s phenomenon. VASA – J Vasc Dis. 2002; 31 (2): 91-94.
Hopkins G et al.:
Double blind cross over study of laser versus placebo in the treatment of tennis elbow. Proc Internat Congr on Lasers, "Laser Bologna". 1985: 210. Monduzzi Editore S.p.A., Bologna.
Hoshino H et al.:
The effect of low reactive level laser therapy in the field of orthopedic surgery. Chronic Pain. 1994; 13: 101-109. (Japanese with English abstract).
Hoteya K et al:.
Effects of a 1 W GaAlAs diode laser in the field of orthopedics. In: Meeting Report: The first Congress of the International Association for Laser and Sports Medicine. Tokyo, 1997. Laser Therapy 1997; 9 (4): 185.
Kaiser C et al.:
Estudio en doble ciego randomizado sobre la eficacia del HeNe en el tratamiento de la sinuitis maxilar aguda: en pacientes con exacerbación de una infección sinusal crónica. Boletín CDL. 1986; 9: 15. Also in Av Odontoestomatol. 1987; 3 (2): 73-76.
Kamikawa K et al.:
Double blind experiences with mid-Lasers in Japan. 1985. Proc Int Congr on Lasers, "Laser Bologna". 1985: 165-169. Monduzzi Editore S.p.A., Bologna.
Kemmotsu M et al.:
LLLT for pain attenuation - the current experience in the pain clinic.In: Progress in Laser Therapy. Eds Oshiro T, Calderhead R G. 1991: 197-200. John Wiley & Sons, Chichester, Engl. ISBN 0-471-93154-3.
Khullar S et al.:
Preliminary study of low-level laser for treatment of long-standing sensory aberrations in the inferior alveolar nerve. J Oral Maxillofac Surg. 1996; 54 (1) :2-7; discussion 7-8.
Khullar S et al.:
Effect of low-level laser treatment on neurosensory deficits subsequent to sagittal split ramus osteotomy. Oral Surgery Oral Medicine Oral Pathology. 1966; 82 (2): 132-8.
Kim J, Lee J.:
Double blind cross-over clinical study of 830 nm diode laser and 5 years clinical experience of biostimul. in plastic & aesthetic surgery in Asians. Lasers Surg Med. 1998; Suppl. 10: 59.
Kinoshita F et al.:
Clinical evaluation of low-energy, semi-conductor laser therapy in oral surgery - a double blind study. Josai Shika Daigaku Kiyo (Bulletin of Josai Dental University). 1986; 15 (3): 735-742. (Japanese with English abstract).
Kouno A et al.:
The evaluation of pain therapy with low powerlaser- Comparative study of thermography and double blind test. Biomedical Thermology. 1993; 13: 102-107.
Kouno A, Fijumasa I.:
The evaluation of pain therapy with low power laser: a comparative study on thermography and double blind test. Thermologie Österreich. 1995; 5 (3): 112 (abstract).
Kosaka R et al.:
Double blind study of low energy diode laser irradiation for chronic pain disorders. J Phys Med. 1993; 4: 156-160.
Laakso E et al.:
Pain scores and side effects in response to low level laser therapy (LLLT) for myofascial trigger points. Laser Therapy. 1997; 2 (9): 67-72.
Lonauer G.:
Controlled double blind study on the efficacy of HeNe-laser beams versus HeNe- plus Infrared-laser beams in the therapy of activated osteoarthritis of finger joints. Clin Experim Rheuma. 1987; 5 (suppl 2) : 39.
Longo L et al.:
Treatment with 904 nm and 10600 nm laser of acute lumbago - double blind control. LASER. J Eur Med Laser Ass. 1988; 1(3):16.
Lucas L et al.:
Low level laser therapy bij decubitus stadium III. Rapport Hoegschool van Amsterdam. 1994.
Lögdberg-Andersson M et al.:
Low level laser therapy (LLLT) of tendonitis and myofascial pains - a randomized, double-blind, controlled study. Laser Therapy. 1997; 2 (9): 79-86.
Mach E et al.:
Helium-Neon (Red Light) Therapy of Arthritis. Rhevmatologia, 1983; 3: 36. (Russian).
Meier J, Kerkour K.:
Traitement laser de la tendinite [Laser treatment of tendinitis]. Médecine et Hygiène. 1988; 46: 907-911.
Mester A.:
Biostimulative effect in wound healing by continous wave 820 nm laser diode. Double-blind randomized cross-over study. Lasers in Med Science, abstract issue July 1988, No 289.
Miyagi K:.
Double-blind comparative study of the effect of low-energy laser irradiation to RA. In: Current awareness of Excerpts Medica. Amsterdam. Elsevier Science Publishers BV. 1989; 25: 315.
Mokhtar B et al.:
A double blind placebo controlled investigation of the hypoalgesic effects of low intensity laser irradiation of the cervical roots using experimental ischaemic pain. Proc. Second Meeting of the International Laser Therapy Assn., "London Laser", Sept 1992, p 61.
Mokhtar B et al.:
The possible significance of pulse repetition rate in lasermediated analgesia: A double blind placebo controlled investigation using experimental ischaemic pain. Proc. Second Meeting of the International Laser Therapy Assn, "London Laser" Sept 1992. p 62.
Molina J et al.:
La laserterapia como coadyuvante en el tratamiento de la A.R. (Artritis Reumatoidea). Boletin C.D.L., Barcelona. 1987; 14: 4-8.
Moore K et al.:
LLLT treatment of post herpetic neuralgia. Laser Therapy. 1988; 1: 7.
Moore K et al.:
The effect of infra-red diode laser irradiation on the duration and severity of postoperative pain. A double-blind trial. Laser Therapy. 1992; 4: 145.
Mousques T.:
Étude en double aveugle des effets du traitment unilateral au laser hélium-néon lors de chirurgies parodontales biláterales simultanés. Quest Odonto-Stomatol. 1986; 11: 245. (French).
Mousques T.:
Étude en double aveugle des effets du hélium-néon en chirurgie parodontale. Quest Odonto-Stomatol 1986; 11: 223. (French).
Neuman I et al.:
Low energy phototherapy in allergic rhinitis and nasal polyposis. Laser Therapy. 1996; 1: 37.
Nivbrant Bo et al.:
Therapeutic laser treatment in gonarthrosis. Acta Orthop Scand. 1989; 60: 231 .Also: [Laser tycks ha effekt pa knaledsartros men vetensskapliga bevis saknas] Lakartidningen. 1992; 89 (11): 859-860. (Swedish).
Ortutay J et al.:
Psoriatic Arthritis Treatment with low power laser irradiation. A double blind clinical study.Laser in Medicine, ed. Waidelich, Munich: 521 - 525 Springer Verlag, 1998.
Oyamada Y et al.:
A double blind study of low power HeNe laser theraphy in rheumatioid arthritis. In: Optoelectronics in Medicine. 1987; p 747-750. Springer Verlag, Berlin (abstract). Complete study in Boletín de CDL. 1988; 17: 8-12.
Palmgren N et al.:
Low-Power Laser Therapy in RA. Lasers in Medical Science. 1989; 4: 193.
Palmgren N et al.:
Low Level Laser Therapy of infected abdominal wounds after surgery. Lasers Surg Med. 1991; Suppl 3:11.
Palmieri B.:
A double blind stratified cross over study of amateur tennis players suffering from tennis elbow using infrared laser therapy. Medical Laser Report. 1984; 1: 3-14.
Poliakova A.et al.:
Laserpuncture in patients with rheumatoids arthritis. Abstracts of ICMART '97 International Medical Acupuncture Symposium, Nicosia, Cyrprus, March 26-29 1997.
Prochazka M, Tejnska R.:
Noninvasive laser therapy of tinnitus: In: A window on the laser medicine world. Proc. SPIE. 1999. Vol. 4166: 223-223. Laser Partner, 2002; 4.
Prochazka M, Hahn A.:
Comprehenvise laser rehabilitation therapy of tinnitus: long term double blind study in a group of 200 patients in three years. Laser Partner, 2002; 51. www.laserpartner.org.
Qadri T, Miranda L, Tunér J, Gustafsson A.
The effects of therapeutic lasers in periodontal inflammation. Swed Den J. Abstract issue, 2003.
Rappl T, Laback C, Quasthoff S, Auer-Grumbach M, Gumpert R, Scharnagl E.:
Low level laser therapy in mild and moderate CTS- a double blind randomised study.
Rochkind S et al.:
Double-blind Randomized Study Using Neurotube and Laser Therapy in the Treatment of Complete Sciatic Nerve Injury of Rats. Proc. 2nd Congr World Assoc. for Laser Therapy, Kansas City, 1998.
Roumeliotis D et al.:
820nm 15mW 4J/cm2, laser diode application in sports injuries. A double blind study. Proc. Fifth Annual Congress British Medical Laser Ass. 1987.
Ryo E et al.:
Double blind test of low energy laser radiation treatment. Evaluation of effectiveness for shoulder stiffness, arthralgia etc. Pain Clinic. 1986; 7: 185-192. (Japanese with English abstract).
Saeki N et al.:
Double blind test for biostimulation effects on pain releif by diode laser. 1989. Laser Surgery; 1066: 93-100.
Sasaki K et al.:
A double-blind controlled study on free amino acid analysis in CO2 laser burn wounds in the mouse model following doses of low incident infrared (830 nm) diode laser energy. Proc. 2nd Meeting if the Internat Laser Therapy Assn., London, 1992: 4.
Sasaki K et al.:
A preliminary double blind controlled study on free amino acid analysis in burn wounds in the mouse following 830 nm diode laser therapy. Laser Therapy. 1997; 2 (9): 59-65.
Sato K et al.:
A double blind assessment of low power laser therapy in the treatment of postherpetic neuralgia. Surgical and Medical Lasers. 1990; 3 (3): 134.
Saunders L.:
The efficiacy of LLLT in supraspinatus tendinitis. Clin Rehab. 1995; 9: 126-134.
Schindl A et al.:
Low intensity laser irradiation improves skin circulation in patients with diabetic microangiopathy. Diabetes Care. 1998; 12 (4): 207-208.
Schindl A, Neuman R.:
Low-intensity laser therapy is an effective treatment for recurrent herpes simplex infection. Results from a randomized double-blind placebo controlled study. J Investigative Dermatology. 1999; 113 (2): 221-223.
Schlager A et al.:
Laser stimulation of acupuncture point P6 reduces postoperative vomiting in children undergoing strabismus surgery. Br J Anesth. 1998; 81 (4): 529-532.
Scudds R et al.:
A double-blind crossover study of the effects of low-power gallium arsenide laser on the symptoms of fibrositis. Physiotherapy Canada.1989; 41: (suppl 3): 2.
Simunovic Z, Trobonjaca T et al.:
Treatment of medial and lateral epicondylitis - tennis and golfer's elbow - with low level laser therapy: a multicenter double blind, placebo controlled clinical study on 324 patients. J Clin Laser Med & Surg. 1998; 16 (3): 145.
Simunovic Z, Trobonjaca T.:
Soft tissue injury during sport activities and traffic accidents - treatment with low level laser therapy. A multicenter double blind, placebo controlled clinical study on 132 patients. Laser Surg Med. 1999; Suppl. 11:5.
Simunovic Z, Trobonjaca T.:
Low level laser therapy in the treatment of osteoarthrosis of joints of the upper extremity: a multicenter, double blind, placebo controlled clinical study of 154 patients. Lasers in Surg Med. Supplement 12, 2000: 7.
Simunovic Z, Trobonjaca T.:
Low level laser therapy in the treatment of cervical syndrome: a multi center, double blind placebod controlled clinical study on 128 patients. Lasers Surg Med. Supplement 12. 2000: 8.
Simunivic Z, Ivankovich A D, Depolo A.:
Wound healing of animal and human body sport and traffic accident injuries using low-level laser therapy treatment: a randomized clinical study of seventy-four patients with control group. J Clin Laser Med Surg. 2000; 18 (2): 67.73.
Slattery K, Amy R, Pinto J et al.:
Treatment of chronic neck and shoulder pain with 635 nm low level laser therapy. A randomized, multi-center, double blind, clinical study on 100 patients. Proc. Second Congress of The North American Ass. for Laser Therapy, Atlanta, GA, March 5-8, 2002.
Snyder-Mackler L et al.:
Effect of helium-neon laser on musculoskeletal trigger points. Physical Therapy. 1986; 66: 1087.
Snyder-Mackler L et al.:
Effect of helium-neon laser irradiation on peripheral sensory nerve latency. Physical Therapy. 1988; 68: 223.
Snyder-Mackler L et al.:
Effect of helium-neon laser irradiation on skin resistance and pain in patients with trigger points in the neck or back. Physical Therapy. 1989; 69: 336.
Soriano F et al.:
Acute cervical pain is relieved with gallium-arsenide (GaAs) laser irradiation. A double-blind preliminary study. Laser Therapy. 1996; 8: 149-154.
Soriano F et al.:
Low level laser therapy response in patients with chronic low back pain. A double blind study. Lasers Surg Med. 1998, Suppl. 10: 6.
Stelian J, Gil I, Habot B et al.:
Improvement of pain and disability in elderly patients with osteoarthritis of the knee treated with narrow-band light therapy. J Am Geriatr Soc. 1992; 40: 23-26.
Taghawinejag M et al.:
Laser-Therapie in der Behandlung kleiner Gelenke bei chronischer Polyarthritis. Z Phys Med Baln Med Klin. 1985; 14.
Taguchi T et al.:
Thermographic changes following laser irradiation for pain. J Clinical Laser Med Surg. 1991; 2(9): 143.
Toya S et al.:
Report on a computer-randomized double blind clinical trial to determine the effectiveness of the GaAlAs (830 nm) diode laser for pain attenuation in selected pain. Laser Therapy 1994; 6:143.
Tsurko V et al.:
Laser therapy and rheumatoid arthritis. A clinical and morphological study. Terap Arkh. 1983; 97. (Russian).
Umegaki S et al.:
Effectiveness of low-power laser therapy on low back pain. Double blind comparative study to evaluate the analgesic effect of low power laser therapy on low-back pain. The Clinical Report. 1989; 23: 2839-2846. (Japanese with English abstract).
Vélez-Gonzalez M et al.:
Treatment of relapse in herpes simplex on labial and facial areas and of primary herpes simplex on genital areas and "area pudenda" with low power HeNe-laser or Acyclovir administred orally. SPIE Proc. 1995; Vol. 2630: 43-50.
Vasseljen O et al.:
Low level laser versus placebo in the treatment of tennis elbow. Scand J Rehab Med. 1992; 24: 37. Also in Physiotherapy. 1992; 5: 329.
Walker J et al:
Relief from Chronic Pain by Low Power Laser Irradiation. Neuroscience Letters. 1983; 43: 339.
Walker J et al:
Temporary suppression of clonus in humans by brief photo-stimulation. Brain Research. 1985; 340: 109.
Walker J et al.:
Laser therapy for pain of RA. Lasers in Surg Med. 1986; 6(12): 171.
Walsh D et al:.
The effect of low intensity laser irradiation upon condution and skin teperature in the superficial radial nerve. Double-blind placebo controlled investigation using experimental ischaemic pain. Proc. Second Meeting of the Internat Laser Therapy Association. "London Laser". 1992.
Willner R et al.:
Low power infrared laser biostimulation of chronic osteoarthritis in hand. Lasers Surg Med. 1985; 5: 149.
Wylie L et al.:
The hypoalgesic effects of low intensity infrared laser therapy upon mechanical pain threshold. Lasers Surg Med. 1995; Suppl 7:9.
Yamaguchi M et al.:
[Clinical study on the treatment of hypersensitive dentine by GaAlAs laser diode using the double blind test]. Aichi Gakuin Daigaku Shigakkai Shi - Aichi-Gakuin Journal of Dental Science. 1990; 28( 2): 703-707. (Japanese).
Yoh K et al.:
A clinical trial for treatment of chronic pain in orthopedic diseases by using 150 mW diode laser system. Result of double blind test. Chronic Pain; 13: 96-100. (Japanese with English abstract).
